:root{--bg:#f4f3eb;--ink:#193c31;--muted:#627168;--line:#d8ded2;--orange:#b75d38;--lime:#d8ec91}*{box-sizing:border-box}body{margin:0;background:var(--bg);color:var(--ink);font-family:Arial,sans-serif;font-size:15px}button,a,input{touch-action:manipulation}button{font:inherit;cursor:pointer}button:focus-visible,a:focus-visible,[tabindex]:focus-visible{outline:3px solid #ce7643;outline-offset:4px}header{max-width:1500px;margin:auto;padding:26px 44px;display:flex;align-items:center;justify-content:space-between;border-bottom:1px solid var(--line)}.brand{letter-spacing:4px;font-weight:800;font-size:23px;text-decoration:none;color:var(--ink)}.brand span{display:block;font-size:8px;letter-spacing:2px;margin-top:5px}.edition,.eyebrow{font-size:11px;font-weight:700;letter-spacing:2px}.outline,.solid{border:1px solid #a8b6a8;border-radius:7px;padding:11px 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button.active{border-color:var(--ink);color:var(--ink);font-weight:700}.panel{display:none}.panel.active{display:block}.sectionbar{display:flex;align-items:center;justify-content:space-between;gap:20px;margin-bottom:23px}h2{font-size:25px;letter-spacing:-.7px;font-weight:600;margin:0 0 8px}h3{line-height:1.3}p{line-height:1.65}.sectionbar p{margin:0;color:var(--muted);font-size:14px}.explorer{display:grid;grid-template-columns:minmax(0,2.4fr) minmax(260px,1fr);gap:18px}.visual{background:#142e26;border-radius:13px;color:#e5ead8;overflow:hidden;display:flex;flex-direction:column;justify-content:space-between}.visualtop{padding:20px 22px;display:flex;justify-content:space-between;font-size:9px;letter-spacing:1.5px;color:#bfceba;gap:10px}.live{color:#d8ec91}svg{width:100%;display:block}svg text{font-family:Arial,sans-serif;fill:#ebefdb;font-size:16px}svg .svlabel{font-size:10px;letter-spacing:1px;fill:#a8bb9e}svg .darktext{fill:#203d30;font-weight:600}svg .small{font-size:12px}.station{cursor:pointer;transition:filter .2s}.station:hover,.station.selected{filter:drop-shadow(0 0 7px #dae3a9)}.legend{display:flex;flex-wrap:wrap;gap:13px;padding:13px 22px 22px;font-size:9px;color:#c0cdb9}.dot{display:inline-block;border-radius:50%;width:7px;height:7px;margin-right:4px}.green{background:#c9e48e}.gold{background:#f2bc75}#stepcard{border:1px solid var(--line);border-radius:13px;padding:26px;background:#e9eee2}.stepnum{font-size:12px;letter-spacing:1px;color:var(--orange);font-weight:bold}#stepcard h3{font-size:25px;letter-spacing:-.7px;margin:21px 0 14px}#stepcard p{font-size:14px}#stepcard .key{border-top:1px solid #cbd6c3;padding-top:15px;font-size:13px}.badge{font-size:10px;letter-spacing:1px;background:#d6e2c8;border-radius:4px;padding:5px 7px;display:inline-block}.steps{display:grid;grid-template-columns:repeat(5,1fr);gap:10px;margin:15px 0 25px}.steps button{background:transparent;color:var(--ink);border:1px solid var(--line);border-radius:7px;text-align:left;padding:15px;font-size:12px;line-height:1.5}.steps button.active{background:var(--ink);color:#e4edcf}.steps button span{display:block;opacity:.6;font-size:10px;margin-bottom:5px}.chain{border-top:1px solid var(--line);padding:8px 0 0}.chain h3{font-size:16px}.chainrow{display:flex;gap:10px;align-items:center;flex-wrap:wrap;font-size:16px;margin:13px 0}.chainrow b{background:#dae5d3;padding:7px 12px;border-radius:6px}.minor{font-size:13px}.minor span{color:var(--muted)}.chain p{font-size:13px;color:var(--muted);max-width:1000px}.cycle{transform-origin:235px 204px;animation:spin 35s linear infinite}.rotor{transform-origin:638px 192px;animation:spin 4s linear infinite}@keyframes spin{to{transform:rotate(360deg)}}.paused *{animation-play-state:paused!important}.presets{display:flex;gap:8px;flex-wrap:wrap;margin-bottom:20px}.presets button{border:1px solid #bcc9b7;border-radius:30px;padding:9px 16px;background:transparent;color:var(--ink);font-size:13px}.presets button.active{background:var(--ink);color:white}.labgrid{display:grid;grid-template-columns:1fr 1.5fr;gap:24px}.controls,.labresult{padding:27px;border:1px solid var(--line);border-radius:13px}.control{margin:21px 0}.control label{display:flex;justify-content:space-between;font-weight:600;font-size:14px}.control small{display:block;color:var(--muted);margin:6px 0}.control input{width:100%;accent-color:#466b48}.disclaimer{font-size:12px;color:var(--muted)}.labresult{background:#e9eee2}.energy{display:flex;align-items:center;gap:23px;border-bottom:1px solid #c7d3c0;padding-bottom:20px}.energy>span{font-size:80px;color:var(--orange);animation:spin 12s linear infinite;line-height:1}.energy small{font-size:10px;letter-spacing:1px}.energy h3{font-size:32px;margin:7px 0}.energy p{margin:0;font-size:13px}.meter{margin:20px 0}.meter label{display:flex;justify-content:space-between;font-size:12px}.track{height:8px;background:#d4ddce;border-radius:4px;margin-top:8px;overflow:hidden}.track div{height:100%;background:#527553;transition:width .4s}.explanation{border-left:3px solid var(--orange);padding-left:18px;font-size:14px}.explanation h3{font-size:16px}.method{margin-top:25px;padding:20px;border:1px solid var(--line);border-radius:8px}.method summary{cursor:pointer;font-weight:600}.method p{font-size:13px;max-width:1050px}.causegrid{display:grid;grid-template-columns:300px 1fr;gap:24px}#causebuttons{display:flex;flex-direction:column;gap:8px}#causebuttons button{background:none;border:1px solid var(--line);border-radius:7px;text-align:left;padding:15px;color:var(--ink)}#causebuttons button.active{background:var(--ink);color:white}#causebody{background:#e9eee2;padding:30px;border-radius:13px}#causebody h3{font-size:27px;margin:14px 0}.causal{display:flex;flex-direction:column;gap:9px;align-items:flex-start;margin:25px 0}.causal span{border:1px solid #a8bba0;background:#f3f5ec;padding:12px 18px;border-radius:6px}.causal i{font-style:normal;margin-left:25px;color:#b2663f}.wide-note{border-top:1px solid var(--line);margin-top:30px;padding:15px 0}.wide-note p{max-width:1100px;color:var(--muted);font-size:14px}.evidencegrid{display:grid;grid-template-columns:repeat(3,1fr);gap:18px}.evidencecard{border:1px solid var(--line);border-radius:10px;padding:24px}.evidencecard h3{font-size:20px}.evidencecard p{font-size:14px;color:var(--muted)}.evidencecard .badge{background:#e9ddc8}.sourceheading{margin-top:30px}.source{display:grid;grid-template-columns:45px 1fr;border-top:1px solid var(--line);padding:16px 0;gap:10px;font-size:13px}.source a{color:var(--ink);text-underline-offset:3px}.source p{margin:5px 0;color:var(--muted)}footer{border-top:1px solid var(--line);display:flex;justify-content:space-between;padding:25px 0;margin-top:45px;font-size:10px;letter-spacing:1px;color:var(--muted)}footer i{margin:0 12px;color:var(--orange)}@media(max-width:950px){header,main{padding-left:22px;padding-right:22px}.intro-note{display:none}.explorer{grid-template-columns:1fr}.labgrid{grid-template-columns:1fr 1.2fr}.steps{gap:6px}.steps button{padding:10px}.evidencegrid{grid-template-columns:1fr}.causegrid{grid-template-columns:230px 1fr}nav{gap:17px;overflow:auto}nav button{font-size:12px}#stepcard h3{margin:12px 0}}@media(max-width:640px){header{padding-top:19px;padding-bottom:19px}.edition{display:none}.brand{font-size:18px}#motion{font-size:11px;padding:9px}.intro{padding-top:26px}h1{letter-spacing:-1.5px}.eyebrow{font-size:9px}.lead{font-size:14px}.sectionbar{align-items:flex-start;flex-direction:column}.sectionbar button{font-size:12px}h2{font-size:23px}.visualtop{font-size:7px;padding:16px 12px}.legend{font-size:8px;padding:12px}.steps{grid-template-columns:repeat(2,1fr)}.labgrid,.causegrid{grid-template-columns:1fr}.causegrid #causebuttons{display:grid;grid-template-columns:1fr 1fr}#causebuttons button{font-size:12px}.energy h3{font-size:26px}.controls,.labresult,#causebody{padding:21px}.energy>span{font-size:58px}footer{gap:20px;line-height:1.8}footer span:last-child{display:none}}@media(prefers-reduced-motion:reduce){*{animation:none!important;transition:none!important}}

#labvisual{margin-top:20px}.stream{animation:stream 1s linear infinite}@keyframes stream{to{stroke-dashoffset:-28}}
nav{gap:17px;overflow-x:auto}nav button{font-size:12px}.genomegrid{display:grid;grid-template-columns:1fr 1.2fr 1.2fr;gap:20px;margin:24px 0}.genomegrid>div{padding:24px;background:#e9eee2;border-radius:10px}.genomegrid strong{display:block;font-size:24px;font-weight:500;margin:16px 0}.genomegrid p{font-size:13px;color:var(--muted);margin-bottom:0}.proteinlayout{display:grid;grid-template-columns:260px 1fr;gap:24px}#proteinbuttons{display:flex;flex-direction:column;gap:7px}#proteinbuttons button,.statebuttons button{border:1px solid #c1ccba;padding:12px 14px;background:transparent;border-radius:6px;text-align:left;color:var(--ink);font-size:13px}#proteinbuttons button.active,.statebuttons button.active{background:var(--ink);color:white}.statebuttons{display:flex;gap:8px;margin-bottom:14px}.proteinbody{padding:28px;background:#e9eee2;border-radius:10px}.proteinbody h3{font-size:28px;margin:17px 0 8px}.proteinbody p{font-size:14px}.proteingene{display:grid;grid-template-columns:1fr 1.4fr;gap:20px;border-top:1px solid #bfcdb8;border-bottom:1px solid #bfcdb8;padding:20px 0;margin:22px 0}.proteingene b{font-size:12px;text-transform:uppercase;letter-spacing:1px}.proteingene p{font-size:13px;line-height:1.8}.mechanismflow{display:flex;justify-content:space-between;gap:10px;align-items:center;background:#193c31;color:#e9eee2;padding:18px;border-radius:6px;font-size:12px}.flowdots{color:#d8ec91;animation:transit 1s infinite linear;font-style:normal;white-space:nowrap}.defective .flowdots{color:#ffc08c;animation-duration:3s}.defective{background:#f0e9dc}.testline{border-top:1px solid #bfcdb8;padding-top:16px}.tablewrap{overflow:auto}table{border-collapse:collapse;width:100%;font-size:13px}th,td{padding:14px;border:1px solid #d1d8ca;text-align:left;line-height:1.5}th{background:#e1e9d9}.verdict{padding:24px;background:#e9eee2;border-radius:10px}.verdict h3{margin:0;font-size:25px}.verdict p{max-width:1000px}.hypothesisrow{display:grid;grid-template-columns:50px 1fr;gap:25px;padding:27px 0;border-bottom:1px solid var(--line)}.hypothesisrow p{max-width:1000px;font-size:14px}.hypnum{font-size:36px;color:#809777}.hypothesisrow h3{font-size:21px}@keyframes transit{50%{opacity:.35}}@media(max-width:800px){.genomegrid{grid-template-columns:1fr}.proteinlayout{grid-template-columns:1fr}#proteinbuttons{display:grid;grid-template-columns:1fr 1fr}.proteingene{grid-template-columns:1fr}.proteinbody{padding:20px}.mechanismflow{flex-wrap:wrap}.hypothesisrow{gap:12px;grid-template-columns:30px 1fr}}
#proteinmap{margin:24px 0}#proteinmap .visual svg{max-height:330px}.mapnode{cursor:pointer}.mapselected{filter:drop-shadow(0 0 6px #f4e5ad)}.refjump{color:inherit;text-underline-offset:3px}.source{scroll-margin-top:24px}
/* Reciprocal cell signalling */
.cellmap{display:grid;grid-template-columns:repeat(3,1fr);gap:18px}.cellmap article{background:#e8ede1;padding:24px;border-radius:12px}.cellchoices{display:flex;flex-wrap:wrap;gap:10px;margin:22px 0}.cellchoices .selected{background:#204b3c;color:#fff}.cellroute{display:grid;grid-template-columns:1fr 48px 1.4fr;align-items:center;background:#17382c;color:#f3f0df;padding:28px;border-radius:12px;gap:16px}.cellroute h3{color:inherit}.cellroute small{letter-spacing:.12em;color:#c7d8b5}.routeflow{font-size:32px;animation:signalpulse 2s ease-in-out infinite}.steroidpath{display:flex;align-items:center;gap:20px;padding:30px 0}.steroidpath>div{flex:1;border:1px solid #738a69;padding:18px;border-radius:10px}.steroidpath b{display:block;font-size:22px;color:#e9c284}.steroidpath small{display:block;margin-top:12px;line-height:1.7}.steroidpath>span{font-size:28px}.visual>p{color:#d8e2cf}.cellmap p{line-height:1.7}@keyframes signalpulse{50%{opacity:.35;transform:translateX(5px)}}.paused .routeflow{animation-play-state:paused}@media(prefers-reduced-motion:reduce){.routeflow{animation:none}}@media(max-width:750px){.cellmap{grid-template-columns:1fr}.cellroute{grid-template-columns:1fr}.routeflow{transform:rotate(90deg)}.steroidpath{flex-direction:column;align-items:stretch}.steroidpath>span{text-align:center;transform:rotate(90deg)}}
.atlaslegend{display:flex;flex-wrap:wrap;gap:8px;margin:18px 0}.atlaslegend span{font-size:11px;letter-spacing:.04em;border:1px solid #cbd5c2;border-radius:6px;padding:9px;background:#e8edde}.atlaslegend .hypmark{border-style:dashed;background:#f3ead8}.atlascontrols{display:flex;gap:24px;flex-wrap:wrap;margin:25px 0}.atlascontrols label{display:grid;gap:9px;font-size:13px;font-weight:bold}.atlascontrols select{padding:13px 35px 13px 14px;border:1px solid #a2b19b;border-radius:8px;background:#fffdf6;color:#193c31;font-size:16px;min-width:250px}.atlasroute{background:#17382c;color:#eef0df;padding:26px;border-radius:12px}.atlasroute h3{color:#e8cb8b;font-size:23px;line-height:1.5}.studygrid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:18px;margin:22px 0}.studycard{background:#e7eddf;border:1px solid #d0dac7;border-radius:12px;padding:23px}.studycard h3{font-size:18px;line-height:1.5}.studycard p{line-height:1.65}.endpoint{border-bottom:1px solid #cbd5c2;padding-bottom:14px}.hypothesisbox{padding:22px;border:2px dashed #ad8553;border-radius:12px;background:#f2ebdc}.branchgrid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:20px}.branchgrid>div{border-left:3px solid #a9bd93;padding:16px}.hormoneatlas hr{border:0;border-top:1px solid #bdcbb0;margin:45px 0}nav{flex-wrap:wrap;overflow:visible}@media(max-width:750px){.studygrid,.branchgrid{grid-template-columns:1fr}.atlascontrols{display:grid}.atlascontrols select{min-width:0;width:100%}nav{flex-wrap:nowrap;overflow-x:auto}}
/* 2.4 · Vernetzte Stoffwechselwege */
.nx-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(min(100%,270px),1fr));gap:18px;margin:22px 0}.nx-card{border:1px solid var(--line,#d5dbcf);border-radius:14px;padding:22px;background:#fafbf4;min-width:0}.nx-card h3{margin-top:0}.nx-controls{display:flex;flex-wrap:wrap;gap:10px;margin:22px 0}.nx-controls button{border:1px solid #a8b8a6;border-radius:9px;padding:12px 16px;background:transparent;color:#214435;cursor:pointer}.nx-controls button.active,.nx-controls button[aria-pressed="true"]{background:#214435;color:#fff}.nx-controls label{display:grid;gap:8px}.nx-controls select{padding:12px;border-radius:8px;border:1px solid #a8b8a6;background:#fff;max-width:100%}.nx-route{background:#173d31;color:#f3f5e9;padding:24px;border-radius:14px;margin:18px 0;line-height:1.8;overflow-wrap:anywhere}.nx-route h3,.nx-route h4{color:inherit}.nx-note{padding:16px 20px;border-left:3px solid #b88347;background:#efefdf;margin:18px 0;line-height:1.65}.nx-grid p,.nx-card p{line-height:1.7}.nx-steps{display:grid;gap:12px;counter-reset:steps;padding:0;list-style:none}.nx-steps li{padding:16px 20px;border:1px solid #bdcbb5;border-radius:10px}.nx-steps li:before{counter-increment:steps;content:counter(steps,decimal-leading-zero) ' · ';font-weight:700;color:#a37440}.nx-audit{margin:24px 0;padding:22px;border:1px solid #bdcbb5;border-radius:14px}.nx-audit summary{cursor:pointer;font-weight:600}button:focus-visible,select:focus-visible,a:focus-visible{outline:3px solid #ba7d43;outline-offset:4px}@media(max-width:700px){.nx-controls button{flex:1 1 140px}.nx-route{padding:18px}.nx-card{padding:18px}}
:root{--ov-line:#779168}
.ov-zoom{border:1px solid var(--line);border-radius:16px;overflow:hidden;background:#fffef8}.ov-levels{display:grid;grid-template-columns:repeat(6,minmax(0,1fr));border-bottom:1px solid var(--line)}.ov-levels button{border:0;border-right:1px solid var(--line);padding:20px 10px;background:transparent;color:var(--ink);text-align:left;font-size:13px;line-height:1.4}.ov-levels button:last-child{border-right:0}.ov-levels button span{display:block;font-size:11px;color:var(--muted);margin-bottom:9px}.ov-levels button[aria-pressed=true]{background:var(--ink);color:#eff4df}.ov-levels button[aria-pressed=true] span{color:#d8ec91}.ov-levelbody{display:flex;align-items:center;justify-content:space-between;gap:25px;padding:26px 30px;min-height:186px}.ov-levelbody p{max-width:760px;line-height:1.65}.ov-levelbody h3{font-size:25px;margin:8px 0}.ov-levelbody button{flex-shrink:0}.ov-caption{font-size:12px;color:var(--muted);line-height:1.6;margin:13px 0 30px}.ov-heading{margin:36px 0 17px}.ov-heading h3{font-size:27px;font-weight:500;margin:10px 0}.ov-heading p{line-height:1.65}.ov-figure{background:#142b23;color:#eaf0df;border-radius:18px;padding:18px;overflow:auto}.ov-svg{display:block;width:100%;height:auto;min-width:690px}.ov-svg text{fill:#eaf0df;font:17px Arial,sans-serif}.ov-svg .ov-strong{font-size:18px;font-weight:bold}.ov-svg .ov-small{font-size:13px;fill:#b9cabb}.ov-svg .ov-dark{fill:#193c31}.ov-svg .ov-node{fill:#294437;stroke:#789783;stroke-width:1}.ov-svg .ov-flow{stroke:#769368;stroke-width:3;fill:none}.ov-svg .ov-signal{stroke:#ce885c;stroke-width:2;stroke-dasharray:7 5;fill:none}.ov-legend{display:flex;justify-content:center;flex-wrap:wrap;gap:25px;font-size:12px;padding:7px 0 12px}.ov-legend span{display:flex;align-items:center;gap:8px}.ov-legend i{width:26px;display:inline-block;border-top:3px solid #769368}.ov-legend i.ov-dashline{border-top:2px dashed #ce885c}.ov-three{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:24px;margin:24px 0}.ov-three article{border-left:2px solid #b4c3a8;padding-left:18px}.ov-three h4{font-size:17px;margin:0 0 8px}.ov-three p{line-height:1.7;font-size:14px;margin:0;color:var(--muted)}.ov-links{display:flex;flex-wrap:wrap;gap:12px;margin:24px 0 32px}.ov-originals{border-top:1px solid var(--line);padding:20px 0}.ov-originals summary{cursor:pointer;color:var(--ink);font-size:18px;font-weight:600;line-height:1.5}.ov-originals summary small{display:block;font-weight:400;font-size:12px;color:var(--muted);margin-left:20px}.ov-originals p{line-height:1.7}.ov-originalgrid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:28px;margin:24px 0}.ov-originalgrid figure{margin:0;padding:22px;background:white;border:1px solid var(--line);border-radius:12px}.ov-originalgrid h4{font-size:20px;margin:0 0 18px}.ov-originalgrid img{width:100%;height:550px;object-fit:contain;display:block;background:white}.ov-originalgrid figcaption{font-size:12px;color:var(--muted)}#overview a{color:inherit;text-underline-offset:3px}@media(max-width:900px){.ov-levels{grid-template-columns:repeat(3,minmax(0,1fr))}.ov-levels button:nth-child(-n+3){border-bottom:1px solid var(--line)}.ov-levelbody{flex-direction:column;align-items:flex-start}.ov-three{gap:18px}.ov-originalgrid img{height:400px}}@media(max-width:600px){.ov-levelbody{padding:22px}.ov-three,.ov-originalgrid{grid-template-columns:1fr}.ov-three article{padding:12px 0 12px 16px}.ov-originalgrid img{height:auto}.ov-heading h3{font-size:23px}.ov-figure{padding:10px}.ov-levels button{font-size:12px}.ov-levelbody h3{font-size:22px}}

/* Short practical introduction; source detail stays optional. */
.atp-everyday{display:grid;grid-template-columns:minmax(190px,.65fr) minmax(0,2fr);gap:0 28px;background:#e7eddf;border:1px solid #c8d3bd;border-radius:12px;margin:0 0 24px;padding:22px 26px}
.atp-everyday-amount{display:flex;flex-direction:column;justify-content:center;align-items:flex-start;padding:4px 24px 16px 0;border-right:1px solid #c8d3bd}
.atp-everyday-amount strong{font-size:clamp(23px,2.4vw,31px);line-height:1.15;font-weight:600;margin:12px 0 6px;letter-spacing:-.7px}
.atp-everyday-amount>span:not(.eyebrow){font-size:15px}.atp-everyday-amount small{font-size:12px;color:#53664e;line-height:1.5;max-width:23ch;margin-top:12px}
.atp-everyday-copy h3{font-size:21px;margin:0 0 10px}.atp-everyday-copy p{font-size:14px;line-height:1.65;margin:0 0 10px}
.atp-everyday-sources{grid-column:1/-1;border-top:1px solid #c8d3bd;padding-top:12px;margin-top:8px;font-size:13px;line-height:1.6}
.atp-everyday-sources summary{cursor:pointer;font-weight:600}.atp-everyday-sources li{margin:8px 0}.atp-everyday-sources a{color:#285846;text-underline-offset:3px}
@media(max-width:650px){.atp-everyday{grid-template-columns:1fr;padding:18px;gap:16px}.atp-everyday-amount{border-right:0;border-bottom:1px solid #c8d3bd;padding:0 0 14px}.atp-everyday-amount small{max-width:none;margin-top:6px}.atp-everyday-sources{margin-top:0}}
